Artichoke Extract is a perennial and is found in the Mediterranean countries as well as in the adjacent parts of central Europe. Artichoke belongs to the aster family having a tuberous root with a stem of five feet height. The flower bud is edible and has large leaves, erect stem and blooms during July to august. This is the cultivated vegetable and is also used as medicine and food. This was also recommended to sweeten unwanted odors. Artichoke flavonoids thrive in rich, deep and well-drained soil. It needs regular feeding and watering, good soil and frost protection from winter. Artichoke is a medicinal herb and the artichoke juice is a liver tonic and the herb has enough abilities to improve bile flow and also to break down the fat. Artichoke leaves have active flavonoids such as luteolin and glucosides as well as other active constituents. Artichoke is used for good digestion and is also used as medicine for treating nausea, dyspepsia, jaundice and hepatitis.

Barberry Bark Extract . Barberry Bark Extract is used for it's main active ingredient, called berberine. Berberine is believed to regulate insulin levels.

Choline Bitartrate , or choline for short, is an essential nutrient involved in many bodily actions such as the structure and function of cells and metabolic functions.

Chromium is a natural trace mineral in human nutrition and is needed for proper metabolism of sugar in humans. It is vital for metabolism of fats and carbohydrates. It helps move blood sugar from the bloodstream into cells to be utilized as energy and turn fats, carbohydrates, and proteins into energy. Chromium helps stimulate fatty acid and cholesterol synthesis, which are needed for brain function and other body processes. It activates numerous enzymes that are required to drive many chemical reactions essential to life. Chromium supplements also improve glucose tolerance in people with Turner's syndrome, a disease associated with glucose intolerance. It is also vital for insulin metabolism. It regulates hunger and decreases cravings.

Dandelion is a bitter diuretic from the Asteraceae family of plants. It performs as a stimulant to the system, concentrated on the urinary organs. When combined with other medicinal herbal agents, it is useful in the treatment of liver and kidney disorders, gallbladder and urinary disorders, jaundice, constipation, cirrhosis, dyspepsia, weaknesses of the heart, eczema and chronic joint and skin problems. Dandelion is also a mild laxative and can be taken in large amounts because it is not poisonous. It promotes good digestion and also increases the appetite.

Inositol - The precise role of Inositol is unknown. Animals deficient in inositol grow poorly and show hair loss. iI occurs naturally in fruits and cereals.

L-Carnitine is a naturally occurring nutrient in the body that helps the body turn fats into energy. It is primarily produced in the liver and kidneys, and is stored in the muscles of the heart, brain, skeleton, and sperm. L-Carnitine is commonly used in supplements used by body builders. It helps increase and boosts the process of burning of fat in the body that gives energy, promotes a healthy cardiovascular system, proper circulation of blood and a healthy liver. It also helps suppress and reduce the appetite. It also helps those with chronic fatigue syndrome, increasing the focus, energy level, and reduces exhaustion.

L-Methionine is an essential amino acid, actually an alpha amino acid, furthermore classified as nonpolar. This proteinogenic amino acid is the only one, besides cysteine, which contains sulfur. Methionine serves as an intermediate of phospholipids, such as phosphatidylcholine, but also lecithin, taurine, carnitine and cysteine. If methionine cannot be properly synthesized, the condition can lead to atherosclerosis. While it must be supplied with diet, this amino acid is deemed a powerful antioxidant, believed to be a scavenger of free radicals, and may assist with the breakdown of fats. Sources of L-Methionine include poultry and related products, including eggs, but also other meats, such as beef, cheese and fish. Methionine adenosyltransferase is converting methionine to S-adenosylmethionine, SAM, which in turn is involved in the creation of creatine, epinephrine, melatonin and further substances.

Milk Thistle (Silybum marianum) extract has been used in treating liver disease and to detoxify the body. Its antioxidant properties enable the liver to function at optimum levels and help in maintaining a good health. So anyone suffering from liver disease including hepatitis, inflamed liver, and jaundice can benefit a great deal from this herb extract that not only regenerates that vital organ but also protects it from common toxins like pesticides, alcohol, pollution, and heavy metal poisoning. Anyone using medications or recreational drugs or performance drugs can use milk thistle seed extract to get relief from the harmful effects of such medications. In addition, it works as an excellent tonic that helps in dealing with stress. Its ability to regulate bowel function makes it a good alternative for people with bowel movements that alternate frequently between constipation and diarrhea.

Phosphatidylcholine is a key phospholipid constituent of cell membranes hepatic lipoproteins and bile. It is commonly used in cell signaling pathways. Phosphatidylethanolamine can prove helpful in treating Alzheimer. Brains affected by Alzheimer comprise fewer synapses and decreased levels of synaptic proteins, membrane phosphatides, choline and DHA. Phosphatidylethanolamine utilizes pyrimidine and a PUFA (for example, docosahexaenoic acid), which can significantly enhance levels of membrane phosphatide and synaptic protein in gerbil brains. Phosphatidylethanolamine also helps regulate homocysteine. It is synthesized by two pathways, CDP-choline pathway and methylation of phosphatidylethanolamine by phosphatidylethanolamine N-methyltransferase (PEMT). Recent research has suggested that PEMT is a significant consumer of methyl groups from S-adenosylmethionine (SAM) and plays an important role in determining homocysteine pools.

Phosphatidylethanolamine, also called Cephalin, is the second most abundant phospholipid in animal and plant lipids. It occurs especially in blood plasma and the white matter of the central nervous system. It is found in all tissues, and is helpful in converting free serine into choline, increasing the levels of acetylcholine and energizing cholinergic pathways. This provides the advantage of producing an increase in memory retrieval efficiency while improving balance and coordination. Phosphatidylethanolamine is a key building block of membrane bilayers as it is often the main lipid component of microbial membranes and can amount to 20% of liver phospholipids and as much as 45% of brain phospholipids.

Taurine is basically an amino acid that is not formed by the body. It is found freely in the bloodstream and in tissues. It is also found in abundance in the skeletal system, the heart and the nervous system. During times of extreme physical activity, the amounts of taurine in the body are depleted. Taurine has a tendency to act as a metabolic transmitter and can also be used as a detoxifying agent. It has been added to a number of products for infants as well. The popular energy drink ‘Red Bull’ is well known for its taurine content. Taurine is also recommended for use by people who suffer from manic depression. Taurine is tested and has proven to be an extremely safe dietary supplement.

Trimethylglycine, which is also known as betaine, due to the source it was discovered in, Beta vulgaris or sugar beets, is an organic compound that is deemed related to trimethylaminoethanol, or choline. To diversify it from other betaines, trimethylglycine is often called glycine betaine as well. Humans generally ingest betaine through their diet, because it is high in content in wheat, whole wheat, shellfish, sugar beets and spinach. It can also be formed in the human body out of choline. As a potential methyl donor, trimethylglycine, or TMG for short, is in the same provider group with Vitamin B12, the folic acid, choline and S-adenosyl methionine, or SAMe. TMG also plays a vital function in the production of carnitine, furthermore it works in protecting kidneys and the liver.

Vitamin B6, which active form pyridoxal phosphate or otherwise known as PLP and pyridoxal-5’-phosphate, is a prosthetic group of tightly bound cofactors responsible for many reactions within the amino acid metabolism and the manipulation of the enzymatic reaction behind the release of glucose from glycogen. Vitamin B6 generally comprises three organic compounds, pyridoxine, pyridoxal and pyridoxamine, all of them heterocyclic organic compounds that are converted in the human body to the active pyridoxal phosphate form. There are three reactions attributed to PLP, namely transamination, alpha elimination and beta elimination. Over one hundred and forty enzyme activities depend on pyridoxal phosphate, neurotransmitter and histamine synthesis, synthesis and function of hemoglobin, and gene expression. As a cofactor, PLP is active in amino acid metabolism, glucogenesis and lipid metabolism.