6,7 Dihydroxybergamottin is a furanocoumarin. This ingredient is generally present in grapefruit. It is also present in bergamot oil from which it derives its name. To a lesser extent it is even available in other citrus fruits and essential oils. Consuming 6, 7 dihydroxybergamottin supplements have an affect on the metabolism of various pharmaceutical drugs. 6, 7 Dihydroxybergamottin inhibits isforms of cytochrome P450 enzyme, especially CYP3A4. It is because of this feature that the enzyme prevents oxidative metabolism of some drugs, which results in accumulation of the drug in the bloodstream. According to some clinical studies 6, 7 dihydroxybergamottin hamper the body’s ability to digest caffeine, thereby extending its presence in the body. Patients under medication must therefore avoid consuming grapefruit and related supplements.

Caffeine, a central nervous system stimulant used in Stacker 3 XPLC as an aid to stay awake, for mental alertness due to fatigue or, in combination with other ingredients for pain relief, and as a power and energy accelerate. Caffeine is available alone as a non-prescription drug over the counter medication, in combination with other non-prescription drugs, and in prescription drug combinations for relief of pain and headache. Like Ephedra, caffeine acts to increase mental alertness while providing additional energy for weight loss and exercise training. Caffeine is more than a stimulant as it goes deep into muscles to provide long lasting power while delaying the onset of muscle fatigue. Also great before working out, caffeine fights fatigue and helps you get ready for your workout. For dieters feeling sluggish that need just a little something extra to get them through the day, caffeine is the obvious no-calorie stimulant solution. Many products containing caffeine anhydrous contain as much caffeine as one or two cups of coffee. It is recommended to limit the use of caffeine containing medications, foods, or beverages while taking caffeine supplements as excess caffeine intake may cause nervousness, irritability, sleeplessness and occasional rapid heart beat.

Capsaicin is commonly found in chilli peppers. Capsaicin contains phyochemicals that fights free radicals and stops therm from damaging the cells that may cause premature aging, cardiovascular ailments, and cancer. Capsaicin is the ingredient that gives chilli peppers its flavour, it is also the active ingredient used in pepper sprays for self-defense. Capsaicin also has antibacterial effects that alleviate the symptoms chronic sinus infections. It works by clearing the mucus from the nose and relieving nasal congestion. Capsaicin is also used to treat arthritis, diabetic neuropathy, and psoriasis. It also has the ability to increase the metabolism that helps burn calories and fats faster. Capsaicin protects against heart problems by reducing the cholesterol and triglycerides. It also dissolves the fibrin that may cause blood clotting.

Yerba Matte is potent and refers to a drink that is brewed with dried leaves. It belongs to the holly family that is an evergreen member. This grows in Peru, Argentina, Brazil and Chile. This is as well found in plenty in Paraguay. The Yerba Mate plant is considered as stimulant, aromatic, astringent, bitter, purgative, diuretic and good for inducing sweat and reducing fever. Yerba mate contains many minerals and vitamins. The Yerba Mate leaf has nutrition and antioxidants in plenty and hence North Americans prepare strong tea using this leaf. Yerba mate powder is used to boost immunity and to detoxify blood, restore hair color, combat fatigue, tone nervous system, stimulate mind, control appetite, retard aging, reduce stress and as well eliminate insomnia. The tea is preferred with sugar or some people add mint and few replace the water with milk. The extraction can be done repetitively so that the properties stay beneficial.

Yohimbine HCL is the active chemical component of the medicinal herb Pausinystalia yohimbe. It is a stimulant drug and is reportedly an aphrodisiac. According to the National Institute of Health (NIH), the standardised form of this chemical is Yohimbine hydrochloride (HCL) and is available as a prescription drug in the United States. Research has shown that yohimbine hydrochloride is effective as a treatment for male impotence. However while yohimbine HCL has been used as a prescription medicine to treat erectile dysfunction controlled studies suggests conflicting results. Apart from male sexual dysfunction, yohimbine HCL has also been used to treat the side effects of antidepressants like female hyposexual disorder etc. It is also used to recall memories in the treatment of post-traumatic-stress-disorder. While there are several uses for yohimbine HCL, there are several side effects too. These include high blood pressure, insomnia, panic attacks, hallucinations, headaches, renal failure, heart disease etc.