6,7 Dihydroxybergamottin is a furanocoumarin. This ingredient is generally present in grapefruit. It is also present in bergamot oil from which it derives its name. To a lesser extent it is even available in other citrus fruits and essential oils. Consuming 6, 7 dihydroxybergamottin supplements have an affect on the metabolism of various pharmaceutical drugs. 6, 7 Dihydroxybergamottin inhibits isforms of cytochrome P450 enzyme, especially CYP3A4. It is because of this feature that the enzyme prevents oxidative metabolism of some drugs, which results in accumulation of the drug in the bloodstream. According to some clinical studies 6, 7 dihydroxybergamottin hamper the body’s ability to digest caffeine, thereby extending its presence in the body. Patients under medication must therefore avoid consuming grapefruit and related supplements.

Caffeine is extracted from coffee and tea during the process of decaffeination. Caffeine Anhydrous can be produced from dimethyl urea and malonic acid. It stimulates the central nervous system, enhancing the focus, concentration, and alertness, and warding off drowsiness. It is a mild diuretic and can also increase the metabolism. It increases the energy level and reduces fatigue. Aside from increasing mental alertness, it also helps in maximizing weight loss training. It stimulates the metabolism that helps the body to burn fat faster and uses the fat as energy. It also provides physical energy and delays the onset of fatigue.

Capsaicin is used in several skin preparations and is used to relieve pain. It is available in the market in various forms such as ointments, creams, gels, liquids, lotions, sticks and pads under marketing names such as Capsagel, Zostrix, Arthricare for Women and Icy Hot Arthritis Treatment. A very astonishing fact is that capsaicin happens to be the active part of chili peppers. Though it is an irritant producing burning sensation on any tissue that comes in contact with it, it depletes substance P. Substance P transmits impulses of pan to the brain. It relieves pain due to diseases such as osteoarthritis, diabetes neuropathy and rheumatic arthritis. Capsaicin has not had any drug interactions till date. But this does not means that it can never have any interaction with any other drug. It is always best to confirm with your doctor if you really need to use capsaicin. Also, it is best to use this drug only in specified quantities.

Yerba Matte, actually yerba maté, as it is called in Brazil, or Ilex paraguariensis in Latin, is a small tree or a shrub which can grow to fifteen meters. It is found naturally in South America, mainly in south of Brazil, Argentina, Paraguay, Uruguay and Chile. Foliage is evergreen, and the flowers are rather small, additionally there is a smallish fruit of red color. A tea like brewing in warm water, not boiling, is a popular drink in the native area, similar social gathering is common, akin to tea time practice in the United Kingdom. Yerba matte has several xanthines alkaloids which are related to caffeine, but although chemically identical to caffeine the mate xanthine cocktail provides different results, for instance it relaxes smooth muscle tissue and stimulates heart tissue. Yerba Matte is a potent ingredient in Stacker 3 XPLC.

Yohimbine HCL, sometimes called yohimbine hydrochloride, yohimbe, or yohimbe bark, is an herbal supplement which serves as a stimulant and possible aphrodisiac for users. Yohimbine has also been shown to be successful in treating erectile dysfunction and impotence in men. It may serve to boost the sex drive of those who take it for aphrodisiac purposes. Some people are recommended to take yohimbine to combat their lower sex drives caused by antidepressants. Yohimbine has also been shown to help blood pressure levels and assist in weight loss. For these reasons, yohimbine is a popular supplement amongst athletes as well as many others wishing to improve their health.